WHO influenza update

http://www.who.int/influenza/surveillance_monitoring/updates/latest_update_GIP_surveillance/en/#.VoT1dQWQUIA.email

CDC on Flu - 'top trending health symptom on Google in 2015

Mers virus vaccine 'a step closer'

Mers virus vaccine 'a step closer'
BBC NEWS - SCIENCE & ENVIRONMENT | 18 DECEMBER 2015
http://pulse.me/s/5miCA4
An effective vaccine to protect against the Mers virus is a step closer, say scientists. Read more

Vaxart Announces Enrollment of First Patient in Influenza B Phase 1 Trial | Vaccines | News Channels

http://pipelinereview.com/index.php/2015121759940/Vaccines/Vaxart-Announces-Enrollment-of-First-Patient-in-Influenza-B-Phase-1-Trial.html

Motavizumab reduces RSV hospitalizations in Native American infants

http://www.healio.com/infectious-disease/respiratory-infections/news/online/%7Ba71bec67-beae-4d07-913a-c95dae42a66f%7D/motavizumab-reduces-rsv-hospitalizations-in-native-american-infants

Posted by Rob Lambkin-Williams

Influenza-Associated Excess Mortality in South Korea

http://www.ajpmonline.org/article/S0749-3797(15)00630-3/abstract

Press Announcements > FDA approves first seasonal influenza vaccine containing an adjuvant

http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm474295.htm

Sanofi Pasteur shares universal influenza vaccine research | Vaccine News

http://vaccinenewsdaily.com/stories/510647422-sanofi-pasteur-shares-universal-influenza-vaccine-research

RSV MUCOSAL VACCINE - KIDO HIROSHI

http://www.freepatentsonline.com/y2015/0297713.html

Palivizumab prophylaxis for respiratory syncytial virus (RSV) in infants with cystic fibrosis (CF) and respiratory illness hospitalizations | European Respiratory Society

http://erj.ersjournals.com/content/46/suppl_59/PA3625

WHO | Influenza update

This update is fascinating. As the flu season in the northern hemisphere approaches its interesting to note that in Australia the dominant viruses have been of the B subtype. Currently most vaccines in the northern hemisphere only protect against one B virus, although a new vaccine which protects against two is available and the Australian government is now switching to this. It seem highly likely that Northern Hemisphere governments will have to follow suit.



http://www.who.int/influenza/surveillance_monitoring/updates/latest_update_GIP_surveillance/en/

VBI Vaccines to Present Update and New Data Supporting its RSV and CMV Vaccine Programs at the World Vaccine Congress Europe - NASDAQ.com

http://www.nasdaq.com/press-release/vbi-vaccines-to-present-update-and-new-data-supporting-its-rsv-and-cmv-vaccine-programs-at-the-20151106-00374

Reference "Influence of Statins on Influenza Vaccine Response..."

J. Infect. Dis., 2015

Influence of Statins on Influenza Vaccine Response in Elderly Individuals.

Black, S; Nicolay, U; Del Giudice, G; Rappuoli, R

Influenza vaccination strategies have targeted elderly individuals because they are at high risk of disease complications and mortality. Statins are a class of drugs used to treat hypercholesterolemia and are frequently used in the elderly population to reduce the risk of cardiovascular disease. However, statins are also known to have immunomodulatory effects that could impact influenza vaccine response. In a post hoc analysis, we performed a cross-sectional observational study nested within a comparative immunogenicity clinical trial of adjuvanted versus unadjuvanted influenza vaccine in elderly persons to evaluate the influence of statin therapy on the immune response to vaccination. Overall, data on >5000 trial participants were available for analysis. Comparison of hemagglutination-inhibiting geometric mean titers to influenza A(H1N1), A(H3N2), and B strains revealed that titers were 38% (95% confidence interval [CI], 27%-50%), 67% (95% CI, 54%-80%), and 38% (95% CI, 28%-29%) lower, respectively, in subjects receiving chronic statin therapy, compared with those not receiving chronic statin therapy. This apparent immunosuppressive effect of statins on the vaccine immune response was most dramatic in individuals receiving synthetic statins. These effects were seen in both the adjuvanted and unadjuvanted vaccine groups in the clinical trial. These results, if confirmed, could have implications both for future clinical trials design, as well as for vaccine use recommendations for elderly individuals.
© The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

PMID: 26516142
URL - http://www.ncbi.nlm.nih.gov/pubmed/26516142?dopt=Citation

Posted by Rob Lambkin-Williams

Reference "Influence of Statins on Influenza Vaccine Response..."

J. Infect. Dis., 2015

Influence of Statins on Influenza Vaccine Response in Elderly Individuals.

Black, S; Nicolay, U; Del Giudice, G; Rappuoli, R

Influenza vaccination strategies have targeted elderly individuals because they are at high risk of disease complications and mortality. Statins are a class of drugs used to treat hypercholesterolemia and are frequently used in the elderly population to reduce the risk of cardiovascular disease. However, statins are also known to have immunomodulatory effects that could impact influenza vaccine response. In a post hoc analysis, we performed a cross-sectional observational study nested within a comparative immunogenicity clinical trial of adjuvanted versus unadjuvanted influenza vaccine in elderly persons to evaluate the influence of statin therapy on the immune response to vaccination. Overall, data on >5000 trial participants were available for analysis. Comparison of hemagglutination-inhibiting geometric mean titers to influenza A(H1N1), A(H3N2), and B strains revealed that titers were 38% (95% confidence interval [CI], 27%-50%), 67% (95% CI, 54%-80%), and 38% (95% CI, 28%-29%) lower, respectively, in subjects receiving chronic statin therapy, compared with those not receiving chronic statin therapy. This apparent immunosuppressive effect of statins on the vaccine immune response was most dramatic in individuals receiving synthetic statins. These effects were seen in both the adjuvanted and unadjuvanted vaccine groups in the clinical trial. These results, if confirmed, could have implications both for future clinical trials design, as well as for vaccine use recommendations for elderly individuals.
© The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

PMID: 26516142
URL - http://www.ncbi.nlm.nih.gov/pubmed/26516142?dopt=Citation


cheers Rob

Sent from a device with a ridiculously small keyboard , apologies for any tyops.

Influenza Vaccine Less Effective in Seniors Taking Statins | Guardian Liberty Voice

http://guardianlv.com/2015/10/influenza-vaccine-less-effective-in-seniors-taking-statins/

Posted by Rob Lambkin-Williams

Quantifying the risk of pandemic influenza virus evolution by mutation and re-assortment — ScienceDirect

http://www.sciencedirect.com/science/article/pii/S0264410X15014711

BMC Infectious Diseases | Full text | Modelling estimates of the burden of Respiratory Syncytial virus infection in adults and the elderly in the United Kingdom

This is an excellent article that emphases that RSV is not just a child's disease


http://www.biomedcentral.com/1471-2334/15/443/

WHO | Monthly Risk Assessment Summary

http://www.who.int/influenza/human_animal_interface/HAI_Risk_Assessment/en/

Visterra Wins Up-to-$204.5M BARDA Contract; Reports Positive Phase IIa Results

https://www.google.com/url?rct=j&sa=t&url=http://www.genengnews.com/gen-news-highlights/visterra-wins-up-to-204-5m-barda-contract-reports-positive-phase-iia-results/81251818/&ct=ga&cd=CAEYACoUMTc2ODA1MTkxMzMwNDg1MDYzMTUyGjA2YjRjOGRhYWEzNzU1OTc6Y29tOmVuOlVT&usg=AFQjCNFcWouGzNVjeLsixVKeizBkPOJ_6A

Controversies in medicine: the rise and fall of the challenge to Tamiflu

http://theconversation.com/controversies-in-medicine-the-rise-and-fall-of-the-challenge-to-tamiflu-38287

This is a fascinating article, it makes one very important point that the Cochrane report reviewed mostly healthy volunteer studies and not those in at risk groups.

A good read.

Dr Rob Lambkin-Williams

Novavax RSV F vaccine trial for women shows promise | Vaccine News

http://vaccinenewsdaily.com/stories/510637784-novavax-rsv-f-vaccine-trial-for-women-shows-promise

Viral infection: Stemming influenza viruses : Nature Reviews Microbiology : Nature Publishing Group

A key goal in influenza research is the design of a universal flu vaccine that affords protection against multiple viral subtypes. Now, two studies report new vaccination strategies that engineer the stem region of haemagglutinin (HA) glycoprotein to elicit antibodies that protect against multiple influenza subtypes in animal models of infection.

http://www.nature.com/nrmicro/journal/vaop/ncurrent/full/nrmicro3553.html

Viewpoint: Why last year's flu vaccine problems must not dent uptake in 2015 | GPonline

http://www.gponline.com/viewpoint-why-last-years-flu-vaccine-problems-not-dent-uptake-2015/respiratory-system/influenza/article/1362213

Respiratory syncytial virus, an ongoing medical dilemma: an expert commentary on respiratory syncytial virus prophylactic and therapeutic pharmaceuticals currently in clinical trials

Respiratory syncytial virus, an ongoing medical dilemma: an expert commentary on respiratory syncytial virus prophylactic and therapeutic pharmaceuticals currently in clinical trials
INFLUENZA AND OTHER RESPIRATORY VIRUSES | 9 JUNE 2015
http://pulse.me/s/4wVLC2
As the most important viral cause of severe respiratory disease in infants and increasing recognition as important in the ... Read more

Respiratory Syncytial Virus (RSV) infections Linked To Respiratory Failure In ... - Medical Research News and Interviews on MedicalResearch.com (blog)

Respiratory Syncytial Virus (RSV) infections Linked To Respiratory Failure In ... - Medical Research News and Interviews on MedicalResearch.com (blog)
RSV - GOOGLE NEWS | 5 JUNE 2015
http://pulse.me/s/4yoEe2
Respiratory Syncytial Virus (RSV) infections Linked To Respiratory Failure In ...Medical Research News and Interviews on ... Read more

Cheers

Rob

Sent from another mobile device with an annoyingly small keyboard, apologies for any typos 

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http://scholar.google.co.uk/scholar_url?url=http://onlinelibrary.wiley.com/doi/10.1111/irv.12346/pdf&hl=en&sa=X&scisig=AAGBfm1bb529k7iHgj_Cu2G-l6VC4rVLRg&nossl=1&oi=scholaralrt

Elevated IL-3 and IL-12p40 levels in the lower airway of infants with RSV-induced bronchiolitis correlate with recurrent wheezing — ScienceDirect

http://www.sciencedirect.com/science/article/pii/S1043466615300272

ERJ | Mobile

http://m.erj.ersjournals.com/content/early/2015/08/20/13993003.00587-2015.abstract


Thanks

Stool screening of Syrian refugees and asylum seekers in Germany, 2013/2014: Identification of Sabin like polioviruses — ScienceDirect

http://www.sciencedirect.com/science/article/pii/S1438422115000715

Favorites

http://onlinelibrary.wiley.com/store/10.1111/irv.12346/asset/irv12346.pdf;jsessionid=0D88653EAE9F2DEE9FA6BC36B5382D7A.f02t02?v=1&t=idqyyq09&s=854904bbb62cc5c43aa105094a1717c0c771db70

Vaccine for Mers 'looks promising'

Vaccine for Mers 'looks promising'
BBC NEWS - HEALTH | 20 AUGUST 2015
http://pulse.me/s/4tJG1d
A prototype vaccine against the lung infection MERS coronavirus shows promising results, scientists say. Read more

Posted by Rob Lambkin-Williams

Visterra Announces Publication of Data Demonstrating the Effectiveness of VIS410 Against Seasonal and Potential Pandemic Influenza Strains - FierceBiotech

http://www.fiercebiotech.com/press-releases/visterra-announces-publication-data-demonstrating-effectiveness-vis410-agai

Posted by Rob Lambkin-Williams

Attenuated Human Parainfluenza Virus Type 1 (HPIV1) Expressing the Fusion F Glycoprotein of Human Respiratory Syncytial Virus (RSV) as a Bivalent HPIV1/RSV Vaccine

http://jvi.asm.org/content/early/2015/07/24/JVI.01380-15.abstract

Posted by Rob Lambkin-Williams

Assessing coughing-induced influenza droplet transmission and implications for infection risk... - Abstract - Europe PubMed Central

http://europepmc.org/abstract/med/26211781


Posted by Rob Lambkin-Williams

Novavax (NVAX) Announces Seasonal Influenza VLP Met Immunogenicity Targets in ... - StreetInsider.com

Novavax (NVAX) Announces Seasonal Influenza VLP Met Immunogenicity Targets in ... - StreetInsider.com
INFLUENZA - GOOGLE NEWS | 30 JULY 2015
http://pulse.me/s/4pZqRU
Novavax (NVAX) Announces Seasonal Influenza VLP Met Immunogenicity Targets in ...StreetInsider.comNovavax (NASDAQ: NVAX) ... Read more

Posted by Rob Lambkin-Williams 

Reinventing the Common Cold Institute for the 21st Century

Reinventing the Common Cold Institute for the 21st Century
Dr Robert Lambkin-Williams
Since Edward Jenner performed the first documented Human Viral Challenge (HVC) study with smallpox on the 14th of May 1796 the utility of such studies has been apparent. In 1931 Sir Christopher Andrews returned from the US where he had observed the use of chimpanzees in the study of influenza. However, as his return coincided with the great depression, funding for similar work in the UK was extremely limited. Sir Christopher therefore decided to enrol students from St Bartholomew's Hospital. He explained to them that as he could not get chimpanzees, he considered the next best thing would be a "Bart's" student. Despite the comment that "they were cheaper than chimpanzees", over 100 students immediately enrolled, but the students had to continue their studies and were not isolated in the same way the chimpanzees had been in the USA]. This confounded any analysis of the data as the investigators could not be certain that the symptoms were not due to any other respiratory viruses acquired in the community. The UK's Medical Research Council (MRC) terminated the work just a year later.
After the conclusion of World War II, a new approach was pioneered by Dr David Tyrell at the Common Cold Institute (CCI). From 1946, volunteers were inoculated by instilling small quantities of virus into their noses. The CCI housed healthy volunteers in relative isolation from other people, thereby reducing the risk of contact with natural sources of infection or of passing on the virus to members of the public. During its time, the unit attracted 20,000 volunteers until its closure in 1989.
The HVC Model using healthy volunteers provides a unique opportunity to describe the viral lifecycle as: the time point of infection is known with certainty, nasal virus shedding can be measured, symptoms are recorded prospectively, and participants are selected with low pre-haemagglutination inhibition (HAI) antibody titres to ensure a statistically significant infection rate with a relatively small number of volunteers.
Post 1989 experimental infection studies continued, with small motels and hotels in the USA substituting for the wooden huts on Salisbury Plain. Such studies contributed to the significant development of the new neuraminidase inhibitors during the 1990's.
We restarted HVC studies in the UK in 2001 and since then we have conducted multiple studies with over 1900 volunteers inoculated with Influenza, Respiratory Syncytial Virus (RSV) or Human Rhinovirus (HRV). We have advanced research for vaccine and antiviral drugs that could save thousands of lives every year.

New Flu Vaccine May Soon Cover All Strains Of Influenza : LIFE : Tech Times - Tech Times

New Flu Vaccine May Soon Cover All Strains Of Influenza : LIFE : Tech Times - Tech Times
INFLUENZA - GOOGLE NEWS | 24 JULY 2015
http://pulse.me/s/4pE27L

Posted by Rob Lambkin-Williams

Tech TimesNew Flu Vaccine May Soon Cover All Strains Of Influenza : LIFE : Tech TimesTech TimesSeasonal influenza causes high ... Read more

--
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Cheers

Rob

Sent from another mobile device with an annoyingly small keyboard, apologies for any typos 

Favorites

Posted by Rob Lambkin-Williams

http://cdn.intechopen.com/pdfs-wm/48684.pdf

What adaptive changes in hemagglutinin and neuraminidase are necessary for emergence of pandemic influenza virus from its avian precursor? - Springer

http://link.springer.com/article/10.1134/S000629791507007X

Posted by Rob Lambkin-Williams

VACCINE AGAINST RSV - Radosevic, Katarina

http://www.freepatentsonline.com/y2015/0196632.html


Thanks


Posted by Rob Lambkin-Williams

A review of respiratory viruses in under 5s

Posted by Rob LW


http://www.jogh.org/documents/issue201501/jogh-05-010408.pdf

WHO | Influenza update

http://www.who.int/influenza/surveillance_monitoring/updates/latest_update_GIP_surveillance/en/

Posted by Rob Lambkin-Williams

Thorax | Mobile

http://m.thorax.bmj.com/content/early/2015/06/19/thoraxjnl-2015-207320.extract


Posted by Rob Lambkin-Williams

Human bocavirus infection as a cause of severe acute respiratory tract infection in children — ScienceDirect

http://www.sciencedirect.com/science/article/pii/S1198743X1500659X


Posted by Rob Lambkin-Williams

22,000 asthma sufferers prescribed potentially deadly medication - Telegraph

http://www.telegraph.co.uk/news/science/science-news/11675702/22000-asthma-sufferers-prescribed-potentially-deadly-medication.html

Posted by Rob Lambkin-Williams

Globally, influenza activity has decreased from its peak of influenza activity in early 2015 to low levels.

http://www.who.int/influenza/surveillance_monitoring/updates/latest_update_GIP_surveillance/en/

South Korea MERS outbreak: Interest

South Korea MERS outbreak: Interest rate cut
http://www.cnn.com/2015/06/11/asia/south-korea-mers-outbreak/index.html


Thanks

Posted by Rob Lambkin-Williams

South Korea to track mobile phones to enforce Mers virus quarantine rules

South Korea to track mobile phones to enforce Mers virus quarantine rules
http://gu.com/p/49htk

Posted by Rob Lambkin-Williams

Fifth Person Dies Of MERS Virus In South Korea

Officials in South Korea say another person has died of Middle East Respiratory Syndrome (MERS), bringing the total number of deaths to five.

Sixty-four people have been infected by the virus since it was first reported in South Korea on 20 May.

Hundreds of schools have closed and hundreds of people quarantined.

Acting Prime Minister Choi Kyung-hwan sought to calm down fears, saying there was no reason to believe that the virus will significantly spread further in the country.

"So far, all the MERS cases have been hospital-associated, and there has been no case of an infection in other social settings. We think we have a chance at putting the outbreak under total control," Mr Choi told a news conference.

While the virus has no vaccine, health experts say it spreads through close contact with infected people and not through the air.

The UN health agency has reported that there's no evidence yet in South Korea of "sustained transmission in the community".

The government announced the names of the 24 hospitals where the MERS patients have been diagnosed or had been treated before their condition was confirmed.

This will allow people who have visited those facilities in recent weeks to report themselves if they are showing symptoms similar to MERS-related illnesses, Mr Choi said.

While the government had earlier identified one hospital in a city south of Seoul where the first MERS case was confirmed, and another in southern Seoul which has been a significant source of infections, it had been reluctant to release the full list of hospitals over concerns that it would cause a disruption in services if people started avoiding them.

The government said it will also strengthen its monitoring of the hundreds of undiagnosed patients who are quarantined at their homes because officials believe they might have contracted the virus.

First identified in humans in 2012, MERS is caused by a coronavirus from the same family as the one that triggered Severe Acute Respiratory Syndrome (SARS).

But MERS has a much higher death rate at 38%, according to World Health Organisation figures.

The South Korean MERS outbreak is traced to a man who returned from a business trip to the Middle East. His wife, who was also infected, has recovered and became the first in the outbreak to be discharged from the hospital, officials said. 

Communication gaps fuel MERS worries in Korea | Science/AAAS | News

http://news.sciencemag.org/asiapacific/2015/06/communication-gaps-fuel-mers-worries-korea?utm_campaign=email-news-latest&utm_src=email

Posted by Rob Lambkin-Williams

MERS, SARS, Ebola: How dangerous are they?

http://www.usatoday.com/story/news/2015/06/03/mers-south-korea-quarantine/28406489/

Posted by Rob Lambkin-Williams

WHO | Recommended composition of influenza virus vaccines for use in the 2015-2016 northern hemisphere influenza season

http://www.who.int/influenza/vaccines/virus/recommendations/2015_16_north/en/

Posted by Rob Lambkin-Williams

Mers case brings back memories of Hong Kong's Sars outbreak | South China Morning Post

http://m.scmp.com/news/hong-kong/health-environment/article/1813336/mers-case-brings-back-memories-hong-kongs-sars

Posted by Rob Lambkin-Williams

Mers spreads

http://app.scmp.com/scmp/mobile/index.html#/article/1813158/hero

Very concerning to see this virus is beginning to spread,

Posted by Rob Lambkin-Williams

New universal influenza vaccines

Posted by Rob Lambkin-Williams

http://www.biomedcentral.com/content/pdf/s12896-015-0164-6.pdf

Oseltamivir reduces clinical illness in households in Bangladesh - The Lancet Infectious Diseases

http://www.thelancet.com/journals/laninf/article/PIIS1473-3099(15)70084-8/fulltext?elsca1=etoc&elsca2=email&elsca3=1473-3099_201506_15_6_&elsca4=Public%20Health%7CInfectious%20Diseases%7CInternal%2FFamily%20Medicine%7CNeuropsychiatry%7CNeurology%7CLancet

Posted by Rob Lambkin-Williams

Soon, a single flu shot may offer universal immunity! - BioSpectrum Asia

http://www.biospectrumasia.com/biospectrum/news/221300/soon-single-flu-shot-offer-universal-immunity

Posted by Rob Lambkin-Williams

Favorites

Posted by Rob Lambkin-Williamshttps://etd.ohiolink.edu/!etd.send_file?accession=wright1431880664&disposition=inline

What We Have Learned of the Influenza A pH1N1 2009/10 pandemic: High Clinical Impact of Human Metapneumovirus and Respiratory Syncytial Virus in Hosp... - PubMed - NCBI

http://www.ncbi.nlm.nih.gov/m/pubmed/25971322/
Posted by Rob Lambkin-Williams

Favorites

Posted by Rob Lambkin-Williams http://deepblue.lib.umich.edu/bitstream/handle/2027.42/111373/hongjy_1.pdf?sequence=1&isAllowed=y

Protection against Influenza A Virus Challenge with M2e-Displaying Filamentous Escherichia coli Phages. - PubMed - NCBI

http://www.ncbi.nlm.nih.gov/pubmed/25973787

Posted by Rob Lambkin-Williams

Geocoding can help spot influenza outbreaks

http://www.healio.com/infectious-disease/influenza/news/online/%7B1352099f-b90a-4f5f-bb74-4ee391af02e5%7D/geocoding-can-help-spot-influenza-outbreaks

Posted by Rob Lambkin-Williams

Vaccines developed for H5N1, H7N9 avian influenza strains

http://medicalxpress.com/news/2015-05-vaccines-h5n1-h7n9-avian-influenza.html


Posted by Rob Lambkin-Williams

WHO | Influenza update

http://www.who.int/influenza/surveillance_monitoring/updates/latest_update_GIP_surveillance/en/


Posted by Rob Lambkin-Williams

Immunogenicity and safety of concomitant MF59-adjuvanted influenza vaccine and 23-valent pneumococcal polysaccharide vaccine administration in older adults — ScienceDirect

http://scholar.google.co.uk/scholar_url?url=http://www.sciencedirect.com/science/article/pii/S0264410X15006179&hl=en&sa=X&scisig=AAGBfm348QToj67rhG_5SG-atUQdaZajHw&nossl=1&oi=scholaralrt

Posted by Rob Lambkin-Williams

The Viral Network: A Pathography of the H1N1 Influenza Pandemic

http://m.aje.oxfordjournals.org/content/early/2015/05/15/aje.kwv113.extract

Jimmunol

http://m.jimmunol.org/content/194/1_Supplement/198.12.short


Thanks


Rob

This email was sent from a mobile device with an annoyingly small keyboard, apologies for any typos

WHO | Human infection with avian influenza A(H7N9) virus – China

http://www.who.int/csr/don/14-May-2015-avian-influenza-china/en/

Posted by Rob Lambkin-Williams

Antiviral medicines for influenza should not be prescribed | Notice-board | Pharmaceutical Journal

http://www.pharmaceutical-journal.com/news-and-analysis/notice-board/antiviral-medicines-for-influenza-should-not-be-prescribed/20068540.article


Posted by Rob Lambkin-Williams

Respiratory Syncytial Virus A Huge Unmet Medical Need.

Emergence of multidrug resistant influenza A(H1N1)pdm09 virus variants in an immunocompromised child treated with oseltamivir and zanamivir

http://m.jid.oxfordjournals.org/content/early/2015/05/04/infdis.jiv245.abstract


Posted by Rob Lambkin-Williams

Jnl Inf Dis

http://m.jid.oxfordjournals.org/content/early/2015/05/04/infdis.jiv263.abstract

Avian influenza puts Thanksgiving at risk

http://mobile.globalmeatnews.com/Industry-Markets/Avian-influenza-puts-Thanksgiving-at-risk


Posted by Rob Lambkin-Williams

Planning for a cohort study to investigate the impact and management of influenza in pregnancy... - Abstract - Europe PubMed Central

http://scholar.google.co.uk/scholar_url?url=http://europepmc.org/abstract/med/25834863&hl=en&sa=X&scisig=AAGBfm0EJGf2jmmJS7dL6x1T6WFVd49W7A&nossl=1&oi=scholaralrt


Thanks


Rob

This email was sent from a mobile device with an annoyingly small keyboard, apologies for any typos

RSV, an on-going medical dilemma: an expert commentary on RSV prophylactic and therapeutic pharmaceuticals currently in clinical trials - Broadbent - Influenza and Other Respiratory Viruses - Wiley Online Library

http://onlinelibrary.wiley.com/doi/10.1111/irv.12313/pdf

Posted by Rob Lambkin-Williams

Challenges in developing a cross-serotype rhinovirus vaccine

http://www.sciencedirect.com/science/article/pii/S1879625715000358

Posted by Rob Lambkin-Williams

Quadrivalent influenza vaccine shows superior immunogenicity vs. trivalent vaccine in young children | Healio Mobile

http://www.healio.com/pediatrics/influenza/news/online/%7B1bd566a8-d82d-4db5-bc63-4d99d27aec2b%7D/quadrivalent-influenza-vaccine-shows-superior-immunogenicity-vs-trivalent-vaccine-in-young-children


Posted by Rob Lambkin-Williams

Respiratory Syncytial Virus Infection in Elderly and High-Risk Adults — NEJM

http://www.nejm.org/doi/full/10.1056/NEJMoa043951

Posted by Rob Lambkin-Williams

Glaucoma treatment: by the highest level of evidence - The Lancet

http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(14)62347-3/abstract?elsca1=etoc&elsca2=email&elsca3=0140-6736_20150404_385_9975_&elsca4=Public%20Health%7CInfectious%20Diseases%7CHealth%20Policy%7CInternal%2FFamily%20Medicine%7CGeneral%20Surgery%7CLancet


Sent from a really small keyboard , so apologies for any typos.

Estimating influenza attack rates in the United States using a participatory cohort : Scientific Reports : Nature Publishing Group

http://www.nature.com/srep/2015/150330/srep09540/full/srep09540.html


Posted by Rob Lambkin-Williams

Estimating influenza attack rates in the United States using a participatory cohort : Scientific Reports : Nature Publishing Group

http://www.nature.com/srep/2015/150330/srep09540/full/srep09540.html


Thanks


Rob

This email was sent from a mobile device with an annoyingly small keyboard, apologies for any typos

No such thing as Man Flu

FluCamp, part of Retroscreen Virology, has been infecting people with flu and common cold viruses for over 15 years (flucamp.com). The work is scientifically robust and has helped develop treatments for both children, healthy adults, those in susceptible groups and the elderly. Whilst conducting this research, in which both male and female volunteers were infected, they discovered something unexpected: that there is no such thing as Man Flu. The analysis conducted by Mr A. Mann builds on work he and the team have previously conducted and presented at earlier conferences, further evidence will be presented at upcoming international conferences."

Dr Rob Lambkin-Williams, senior virologist at FluCamp and Retroscreen commented " There are many myths about colds and flu and it's great to put this one to rest!

Flu vaccination during pregnancy is safe an excellent review article.

http://www.sciencedirect.com/science/article/pii/S0264410X15002686

This paper is an excellent review of 19 papers and concludes that influenza vaccination is important in pregnant women and there is no evidence of a safety risk, but further research is needed.

Posted by Rob Lambkin-Williams

Seasonal influenza vaccination rates must be tackled at EU level | The Parliament Magazine

https://www.theparliamentmagazine.eu/articles/opinion/seasonal-influenza-vaccination-rates-must-be-tackled-eu-level

Posted by Rob Lambkin-Williams

The Viroblog 2.0

We know that many people enjoy the viroblog and the links we post, however we now intend to expand things substantially. We intend to write weekly editorial articles and invite contributions from everyone.

Many thanks , Rob LW

In addition;

Retroscreen Virology appoints Branch Communications as UK Social Lead Agency

Retroscreen is delighted to announce its appointment of Branch Communications as its lead retained Social Media agency in the UK.
Following the agency's development and presentation to the business of a fully integrated social media plan last year, Retroscreen has charged Branch Communications with handling all of its digital social marketing activity which includes the creation and development of social media communities on Google Plus, Twitter, Facebook and YouTube.
The business is looking forward to leveraging the creativity of Branch Communications in order to reach out and interact with its online following in an original and relevant way. Branch will produce news, views and content designed specifically to appeal to its varied and diverse target audiences which include staff, pharmaceutical companies that wish to use Retroscreen's services and those considering volunteering for its FluCamp clinical trials.

Influenza Type B overtakes A in Colorado during 2015, but still well below peak - The Denver Channel

Influenza Type B overtakes A in Colorado during 2015, but still well below peak - The Denver Channel
INFLUENZA - GOOGLE NEWS | 14 MARCH 2015
http://pulse.me/s/3EJlY5


The Denver ChannelInfluenza Type B overtakes A in Colorado during 2015, but still well below peakThe Denver Channel... Weld ... Read more

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Cheers

Rob

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Can universal vaccines knock out 'slowpoke' flu? - Futurity

http://www.futurity.org/flu-vaccine-epidemics_876692/

Posted by Rob LW

WHO | Human infection with avian influenza A(H7N9) virus – China

http://www.who.int/csr/don/11-march-2015-avian-influenza-china/en/

Influenza hits older adults hard this season | American Pharmacists Association

https://www.pharmacist.com/influenza-hits-older-adults-hard-season


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Strains of swine flu need universal vaccine | mydigitalfc.com

http://www.mydigitalfc.com/industry/strains-swine-flu-need-universal-vaccine-867

Epigenetic study highlights drug targets for allergies and asthma

http://www3.imperial.ac.uk/newsandeventspggrp/imperialcollege/newssummary/news_17-2-2015-10-30-48

Characterization of a large cluster of influenza A(H1N1)pdm09 virus cross-resistant to oseltamivir and peramivir during the 2013/2014 influenza season in Japan

http://aac.asm.org/content/early/2015/02/10/AAC.04836-14.abstract


Thanks


Rob

This email was sent from a mobile device with an annoyingly small keyboard, apologies for any typos

Vaxin acquires Immune Targeting Systems in all-stock deal | BioPrepWatch.com

http://bioprepwatch.com/news/vaxin-acquires-immune-targeting-systems-stock-deal/340939/

Flu Season 2015: Influenza-Related Illnesses Tied To Surge In Hospital ... - International Business Times

Flu Season 2015: Influenza-Related Illnesses Tied To Surge In Hospital ... - International Business Times
INFLUENZA - GOOGLE NEWS | 9 FEBRUARY 2015
http://pulse.me/s/3twLqt


International Business TimesFlu Season 2015: Influenza-Related Illnesses Tied To Surge In Hospital ...International Business ... Read more

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Key to blocking influenza virus may lie in a cell's own machinery

http://m.medicalxpress.com/news/2015-02-key-blocking-influenza-virus-cell.html

ESWI (the flu community) news bulletin

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The ESWI News Bulletin offers you a selection of influenza-related articles collected from a range of media sources. It does not represent the opinions of ESWI or its members.
Kindly e-mail any comments or questions regarding the ESWI News Bulletin to info@eswi.org<mailto:info@eswi.org>.





Tamiflu is effective against influenza, major study finds


New analysis of efficacy data confirms that timely administration of the antiviral influenza drug Tamiflu considerably reduces the impact of an influenza infection in adults. The study results have now been published in The Lancet.
Read the Lancet article<http://email.ettbioclosingconference.eu/usbsalauqqwwapauhbafawsue/click.php>
Read the press statement<http://email.ettbioclosingconference.eu/usbuaiauqqwwacauhbaiawsue/click.php>





'People with diabetes benefit from flu vaccination'


Anne Felton, President of the Foundation of European Nurses in Diabetes (FEND) says people with diabetes can benefit from vaccination against flu and other infectious diseases.
Read more<http://email.ettbioclosingconference.eu/usbearauqqwwavauhbaaawsue/click.php>





Council of the European Union conclusions on vaccination


On 1 December 2014, the Council of the European Union adopted conclusions on vaccinations as an effective tool in public health. The Conclusions recognize that an evidence-based, cost-effective, safe and efficient immunization system is an integral part of a well-functioning health system.
Read more<http://email.ettbioclosingconference.eu/usbmatauqqwwavauhbagawsue/click.php>





Eurosurveillance Rapid Communication


Start of the 2014/15 influenza season in Europe: drifted influenza A(H3N2) viruses circulate as dominant subtype
Read the full communication<http://email.ettbioclosingconference.eu/usbjakauqqwwaoauhbazawsue/click.php>



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CDC issues travel notice for China due to H7N9 avian influenza | Outbreak News Today

http://outbreaknewstoday.com/cdc-issues-travel-notice-for-china-due-to-h7n9-avian-influenza-34414/


Thanks


Rob

This email was sent from a mobile device with an annoyingly small keyboard, apologies for any typos

Flu Jab Found To Work In Just 3% Of Cases

The flu vaccine issued this winter is estimated to work in just 3% of cases, Public Health England (PHE) has revealed.

That compares to a typical past effectiveness of 50%.

According PHE, the "low protection" rate is a result of a "mismatch" between the influenza strain used to make the vaccine and the strain doing the rounds this winter.

It said there has been a genetic "drift" in the virus which had also been recorded in studies in the US and Canada.

Deputy chief medical officer John Watson said: "We do see 'drift' in the flu virus from time to time, but even so, I want to reassure people that it is still the best overall way to protect yourself and your family from flu, along with good hand hygiene.

"Antiviral drugs are available and effective, and doctors should prescribe them for those at greatest risk of becoming seriously ill due to flu."

He added that "the latest data show that levels of flu are generally decreasing in the UK".

PHE's findings were based on data from more than 1,300 patients.

The author of the study and PHE's head of flu surveillance, Dr Richard Pebody, said it is impossible to anticipate whether such a drift is likely to occur when determining which strains of flu virus should be included in the next vaccine.

"It's not possible to fully predict the strains that will circulate in any given season, and there is always a risk of a drift occurring as we have seen this year.

"However, it's important to be aware that this does not occur every season.

"Flu vaccine is still the best protection we have against an unpredictable virus which can cause severe illness and deaths each year among at-risk groups, including older people, pregnant women and those with a health condition, even one that is well managed.

"Throughout the last decade, there has generally been a good match between the strains of flu in the vaccine and those that subsequently circulate, so it's crucial that these results do not discourage people in at-risk groups from having flu vaccination now, or in the future."

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Tamiflu DOES halt the spread of influenza, major review finds - Telegraph.co.uk

Tamiflu DOES halt the spread of influenza, major review finds - Telegraph.co.uk
INFLUENZA - GOOGLE NEWS | 30 JANUARY 2015
http://pulse.me/s/3kGc9n


Telegraph.co.ukTamiflu DOES halt the spread of influenza, major review findsTelegraph.co.uk"Our meta-analysis provides ... Read more

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Rob

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Higher death rate 'driven by flu' - BBC News

http://m.bbc.co.uk/news/health-31124320


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The Tamiflu fiasco and lessons learnt Gupta YK, Meenu M, Mohan P - Indian J Pharmacol

http://www.ijp-online.com/article.asp?issn=0253-7613;year=2015;volume=47;issue=1;spage=11;epage=16;aulast=Gupta


Thanks


Rob

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Oseltamivir treatment for influenza in adults: a meta-analysis of randomised controlled trials - The Lancet

http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(14)62449-1/abstract

Posted by Rob LW

Why Is Influenza So Difficult to Prevent and Treat?

Why Is Influenza So Difficult to Prevent and Treat?
MEDSCAPE.COM
http://pulse.me/s/3ld2W7

Study maps travel of H7 influenza genes

http://m.medicalxpress.com/news/2015-01-h7-influenza-genes.html

Stuff

http://i.stuff.co.nz/national/health/65285167/mutations-delay-influenza-vaccine

Health Canada Clears Immunovaccine to Conduct Phase I Clinical Trial of Respiratory Syncytial Virus (RSV) Vaccine - MarketWatch

http://www.marketwatch.com/story/health-canada-clears-immunovaccine-to-conduct-phase-i-clinical-trial-of-respiratory-syncytial-virus-rsv-vaccine-2015-01-20-7173213


Posted by Rob LW

Influenza Vaccine May Protect Against Guillain-Barre Syndrome

http://www.medscape.com/viewarticle/838208

Posted by Rob LW

Seasonal Influenza Vaccine Only 23% Effective This Year

http://www.medscape.com/viewarticle/838241

Posted by Rob LW

GEN | News Highlights:Brain Protein May Lead to Novel Flu Therapies

http://www.genengnews.com/gen-news-highlights/brain-protein-may-lead-to-novel-flu-therapies/81250791/


Cheers

Rob

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Order Antivirals Before Influenza Is Lab-Confirmed, CDC Says

http://www.medscape.com/viewarticle/837916

BC 2015 influenza outbreak approaching 10-year maximum for medical visits - CBC.ca

BC 2015 influenza outbreak approaching 10-year maximum for medical visits - CBC.ca
INFLUENZA - GOOGLE NEWS | 3 JANUARY 2015
http://pulse.me/s/3eWsUj

Flu shot won't protect against influenza A - WBNG-TV

Flu shot won't protect against influenza A - WBNG-TV
INFLUENZA - GOOGLE NEWS | 3 JANUARY 2015
http://pulse.me/s/3gKSeo


WBNG-TVFlu shot won't protect against influenza AWBNG-TVDoctors said this year, however, the strain that's causing the ... Read more