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Sunday 22 December 2013

Fwd: PRO/EDR> Influenza (67): USA (TX) H1N1




INFLUENZA (67): USA (TEXAS) H1N1
********************************
A ProMED-mail post
<http://www.promedmail.org>
ProMED-mail is a program of the
International Society for Infectious Diseases
<http://www.isid.org>

Date: Fri 20 Dec 2013
Source: Texas Department of State Health Services (DSHS) [summ.,
edited]
<http://www.dshs.state.tx.us/news/releases/Influenza-Health-Alert-122013.pdf>


Influenza health alert
----------------------
Statewide influenza-like illness (ILI) activity continues to increase
and is above baseline levels. ILI intensity is high in Texas, and
influenza is now widespread. All Texas regions have reported
laboratory confirmed influenza. Over 90 per cent of positive influenza
tests reported from Texas laboratories have been typed as influenza A.
Of those influenza A viruses that have been subtyped, 90 per cent have
been the 2009 pandemic H1N1 subtype. This subtype of influenza is
included in this season's [2013-14] influenza vaccine. No novel
influenza cases have been reported in Texas. No antiviral resistant
influenza strains have been reported in Texas.

Background
----------
Influenza viruses can be spread by large respiratory droplets
generated when an infected person coughs or sneezes in close proximity
to an uninfected person. Symptoms can include fever, dry cough, sore
throat, headache, body aches, fatigue, and nasal congestion. Among
children, otitis media, nausea, vomiting, and diarrhea are common.
Most people generally recover from illness in 1-2 weeks, but some
people develop complications and may die from influenza. The highest
rates of influenza infection occur among children; however, the risks
for serious health problems, hospitalizations, and deaths from
influenza are higher among people 65 years of age or older, very young
children, and people of any age who have medical conditions that place
them at increased risk for complications from influenza.

Vaccination
-----------
Everyone who is at least 6 months of age should get a flu vaccine this
season [2013-14]. It is not too late for vaccination. There are
several flu vaccine options available for the 2013-2014 flu season.
All these vaccines contain the currently circulating H1N1 strain. DSHS
[Department of State Health Services] does not recommend one flu
vaccine over another, although there are special indications for some
(such as a high-dose inactivated trivalent vaccine approved for
persons age 65 years and older).

Rapid Lab Test
--------------
Rapid influenza diagnostic tests (RIDTs) can be useful to identify
influenza virus infection, but false negative test results are common
during influenza season. Clinicians should be aware that a negative
RIDT result does NOT exclude a diagnosis of influenza in a patient
with suspected influenza. When there is clinical suspicion of
influenza and antiviral treatment is indicated, antiviral treatment
should be started as soon as possible, even if the result of the RIDT
is negative, without waiting for results of additional influenza
testing.

Treatment: oseltamivir and zanamivir are chemically related antiviral
medications known as neuraminidase inhibitors that have activity
against both influenza A and B viruses. Early antiviral treatment can
shorten the duration of fever and illness symptoms, may reduce the
risk of complications and death, and may shorten the duration of
hospitalization. Clinical benefit is greatest when antiviral treatment
is administered early, especially within 48 hours of influenza illness
onset. Decisions about starting antiviral treatment should not wait
for laboratory confirmation of influenza.

Antiviral treatment is recommended as early as possible for any
patient with confirmed or suspected influenza who
- is hospitalized,
- has severe, complicated, or progressive illness,
- is at higher risk for influenza complications.

Persons at higher risk for influenza complications recommended for
antiviral treatment include:
- children aged younger than 2 years,
- adults aged 65 years and older,
- persons with chronic pulmonary (including asthma), cardiovascular
(except hypertension alone), renal, hepatic, or hematological disease
(including sickle cell disease); metabolic disorders (including
diabetes mellitus); or neurologic and neurodevelopment conditions
(including disorders of the brain, spinal cord, peripheral nerve, and
muscle such as cerebral palsy, epilepsy [seizure disorders], stroke,
intellectual disability [mental retardation], moderate to severe
developmental delay, muscular dystrophy, or spinal cord injury),
- persons with immunosuppression, including that caused by medications
or by HIV infection,
- women who are pregnant or postpartum (within 2 weeks after
delivery),
- persons aged younger than 19 years who are receiving long-term
aspirin therapy.
- American Indians/Alaska Natives.
- persons who are morbidly obese (that is, body-mass index is equal to
or greater than 40).
- residents of nursing homes and other chronic-care facilities.

Clinical judgment, on the basis of the patient's disease severity and
progression, age, underlying medical conditions, likelihood of
influenza, and time since onset of symptoms, is important when making
antiviral treatment decisions for high-risk outpatients.

Additional details regarding antiviral treatment can be found at
<http://www.cdc.gov/flu/professionals/antivirals/summary-clinicians.htm>.

In Texas, influenza-associated pediatric mortality is required to be
reported within one work day. Clusters or outbreaks of any disease,
including influenza, should be reported immediately. Reports of
influenza-associated pediatric mortality and influenza or
influenza-like illness outbreak should be made to your local health
department or to 1-800-705-8868.

--
communicated by:
ProMED-mail
<promed@promedmail.org>

[The correspondent has added the following commentary in relation to
the information above. "This outbreak now appears to involve an H1N1
virus. The vaccine inefficacy statement from the County health
authorities press release highlights, coupled with the apparent
unreliability of rapid diagnostic tests cited in media reports,
suggests to me that H1N1 virus circulating in Texas may be a new [more
virulent ?] drifted or reasserted strain. The current Texas state flu
bulletin for week of 7-14 Dec 2013 issued today (20 Dec 2013) does not
seem to discuss this issue
<http://www.dshs.state.tx.us/idcu/disease/influenza/surveillance/2014/>."

It seems likely that the fatalities observed in Texas are due to a
possibly more virulent strain of the seasonal H1N1 influenza virus,
rather than a novel pathogenic agent. Further information is awaited
to substantiate this conclusion. - Mod.CP]

[See Also:
Undiagnosed respiratory illness - USA (02): (TX) fatal, H1N1 influenza
conf
Undiagnosed respiratory illness - USA: (TX) fatal 20131218.2124064]
.................................................cp/mj/s
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China Confirms H5N2 Bird Flu Outbreak in Hebei

http://english.cri.cn/6909/2013/12/21/2743s804476.htm


Posted by Rob LW

Saturday 7 December 2013

NanoViricides, Inc. Reports Excellent Safety Profile of Its Broad-Spectrum ... - PharmiWeb.com (press release)



NanoViricides, Inc. Reports Excellent Safety Profile of Its Broad-Spectrum ... - PharmiWeb.com (press release)
INFLUENZA - GOOGLE NEWS | 2 DECEMBER 2013
http://pulse.me/s/IJPnr
NanoViricides, Inc. Reports Excellent Safety Profile of Its Broad-Spectrum ...PharmiWeb.com (press release)No overt adverse ... Read 

Saturday 5 October 2013

CureVac, Janssen partner to develop mRNA-based influenza vaccine - Pharmaceutical Business Review

CureVac, Janssen partner to develop mRNA-based influenza vaccine

PBR Staff Writer Published 04 October 2013

Germany-based clinical stage biopharmaceutical firm CureVac has entered into collaboration and licensing agreement with Janssen Pharmaceuticals to develop a messenger RNA (mRNA)-based influenza vaccine.

The deal will see CureVac collaborate with Crucell Holland, a member of the Janssen Pharmaceuticals, on the development of an influenza vaccine based on its RNActive technology.

Under the deal, CureVac will develop optimized RNActive vaccines based on Crucell's antigen sequences which will be tested in several models.

So far, RNActive vaccines based on CureVac's technology platform have showed better efficacy and safety in many clinical trials.

In order to develop new and effective mRNA vaccines, CureVac is combining both the antigenic and adjuvant properties of mRNAs.

RNActive vaccines consist of modified and formulated mRNA with three distinct features: strong antigen expression, increased stability and enhanced immune-stimulatory activity.

Compared to conventional methods, the RNActive technology provides faster generation of vaccines.

Posted by Rob LW

Saturday 24 August 2013

BBC News: Deadly virus found in tomb bat

Deadly virus found in tomb bat

The Mers coronavirus has been detected in a bat in Saudi Arabia, close to the home of the first victim, scientists report.

Read more:
http://www.bbc.co.uk/news/health-23793649


Posted by Rob LW

Saturday 17 August 2013

Friday 9 August 2013

Mers: Coronavirus May Have Come From Camels

Mers: Coronavirus May Have Come From Camels

The Mers virus, which has also been called the coronavirus, has killed 46 people out of a total of 94 it has infected.

It has so far mainly affected the Middle East, but one patient died in Birmingham after contracting the virus from a relative who had come from the region.

Now researchers say they believe the Arabian camel may be a possible host of the deadly virus, officially called the Middle East Respiratory Syndrome Coronavirus (Mers-CoV).

The exact origins of the virus have baffled scientists who have been working hard in a bid to halt its spread.

With the disease shown to have been spread by human-to-human contact, there are fears that it could spread rapidly once the annual Hajj pilgrimage to Saudi Arabia gets underway in October.

It is one of the deadliest viruses yet come across and scientists are worried that if it mutates into a form that moves easily between people, it could wipe out millions.

Now an international team says blood tests have found antibodies against the disease in camels from Oman, meaning they had at some point been infected with Mers, or a closely-related virus.

The findings suggest that Arabian or dromedary camels "may be one reservoir of the virus that is causing Mers in humans", said a statement that accompanied the study published in The Lancet Infectious Diseases journal.

Saudi Arabia has been forced to restrict visas for the 2013 Hajj so far. Millions of Muslims typically flock to the holy sites of Mecca and Medina every year.

Scientists had thought that, like its cousin virus Sars, which killed hundreds of people in Asia 10 years ago, Mers may originate in bats.

They now believe, however, that it is unlikely the nocturnal creatures are to blame, but that an intermediary "reservoir" animal is involved.

There is anecdotal evidence of patients having been in contact with camels or goats, which has now been further confirmed by the study.

In carrying out their study, the team took blood from 50 camels from across Oman and another 105 in the Canary Islands, as well as llamas, alpacas, bactrian camels, cattle, goats and sheep from the Netherlands, Chile and Spain.

They found Mers-like antibodies in all of the Omani camels and at lower levels in 15 of those from the Canary Islands.

The paper's senior author Marion Koopmans, of the Netherlands' National Institute of Public Health and the Environment, said: "What it means is that these camels some time ago have come across a virus that is very similar to Mers-CoV."

But she said the study had not been able to tell when the animals had been exposed, or whether it was the exact same virus.

"For that, studies are needed that collect the right samples from camels while they are infected," said Ms Koopmans. Other animals from the Middle East, like goats, must also be tested.

There are an estimated 13 million dromedary camels in the world today - all but a few are domesticated and most are in Africa and the Middle East.

Mers has claimed lives in Saudi Arabia, Jordan, Qatar, the United Arab Emirates and Tunisia, as well as among people known to have had contact with infected people from the Middle East in France, Germany, Italy, and the UK.

Monday 29 July 2013

Fwd: PRO/AH/EDR> Influenza (43): USA (IN, OH) A(H3N2)v

Posted by Rob LW 


INFLUENZA (43): USA (INDIANA, OHIO), A(H3N2)V
*********************************************
A ProMED-mail post
<http://www.promedmail.org>
ProMED-mail is a program of the
International Society for Infectious Diseases
<http://www.isid.org>

Date: Sun 28 Jul 2013
Source: Global Dispatch, Outbreak News [edited]
<http://www.theglobaldispatch.com/indiana-and-ohio-report-new-h3n2v-human-swine-flu-cases-brings-total-to-14-for-2013-2013/>


In a follow up to a 4 Jul 2013 report, the Centers for Disease Control
and Prevention (CDC) says 2 new human infections with influenza A
(H3N2) variant (H3N2v) virus were reported to CDC during week 29, one
in Indiana and one in Ohio. This brings the total cases this year
[2013] to 14, with Indiana reporting 13 cases.

The CDC reports no hospitalizations or deaths have occurred. In
addition, no ongoing human-to-human transmission has been identified,
and all 14 cases have reported close contact with swine in the week
prior to illness onset. CDC officials add: "Additional cases may be
identified as the investigation continues." The Ohio Department of
Health reminded its citizens to practice good hygiene when visiting
livestock exhibits this summer [2013], in a recent new release.

"Individuals should always wash hands with soap and water before and
after petting or touching any animal. Never eat, drink, or put
anything in your mouth in animal areas. Parents and caregivers are
encouraged to leave strollers outside the animal exhibits and carry
small children. Older adults, pregnant women, young children, and
people with weakened immune systems should consider avoiding animal
areas," health officials said.

Type A influenza viruses, including H3N2 and H3N2v, commonly infect
swine, causing outbreaks among swine herds. Most of the type A
influenza viruses that infect swine are genetically very different
from human (seasonal) influenza viruses. While these variant influenza
viruses seldom infect humans, such infections can and do occur. In
fact, influenza viruses can spread both from swine to humans and from
humans to swine.

Out of the 2012 total of 309 H3N2v cases, Indiana and Ohio accounted
for the bulk of the cases with 138 (45 percent) and 107 (35 percent)
cases, respectively.

[Byline: Robert Herriman]

--
Communicated by:
ProMED-mail from HealthMap Alerts
<promed@promedmail.org>

[It is clear that the A/H3N2v virus is still widespread in swine in
the states of Indiana and to a lesser extent Ohio. However, the number
of infections occurring as a consequence of visits to livestock fairs
appears to have declined, indicating that previous warnings are being
heeded. No instance of human-to-human transmission has been recorded
so far. - Mod.CP

HealthMap/ProMED-mail maps for Indiana and Ohio can be accessed at:
<http://healthmap.org/r/2qty> and <http://healthmap.org/r/2uyX>,
respectively.]

[see also:
Influenza (40): USA, A(H3N2)v, CDC Health Advisory 20130706.1810766
Influenza (39): USA (IN) A(H3N2)v, alert 20130627.1795810
2012
----
Influenza (29): H3N2v cross-reactive antibodies 20120412.1099325
Influenza (28): USA (UT), H3N2v isolation 20120412.1098447
Influenza (25): H3N2v, pathogenesis & transmission 20120407.1093271
Influenza (12): H3N2v pandemic potential 20120222.1049306
Influenza (29): H3N2v cross-reactive antibodies 20120412.1099325
Influenza (28): USA (UT), H3N2v isolation 20120412.1098447
Influenza (25): H3N2v, pathogenesis & transmission 20120407.1093271
Influenza (12): H3N2v pandemic potential 20120222.1049306
2011
----
Influenza (78): USA, swine-origin H3N2 reassortants update
20111224.3669
Influenza (76): USA, two novel influenza A viruses 20111210.3563
Influenza (74): swine-origin H3N2 reassortant, vaccine candidate
20111203.3526
Influenza (72): Europe, swine-origin H3N2 reassortant, risk assessment
20111130.3494
Influenza (71): USA (IA) swine-origin H3N2 reassortant, WHO
20111125.3448
Influenza (70): USA (IA) swine-origin H3N2 reassortant 20111124.3438
Influenza (69): USA (IA) swine-origin H3N2 reassortant 20111123.3430
Influenza (68): Hong Kong swine-origin H3N2 reassortant 20111119.3411
Influenza (66): USA swine-origin H3N2 reassortant, update
20111105.3298
Influenza (63): USA (ME, NOT NH) corr. 20111106.3307
Influenza (63): USA (ME, NOT NH) swine-origin H3N2 reassortant
20111102.3260
Influenza (60): USA (ME) swine-origin H3N2 reassortant 20111021.3134]
.................................................sb/cp/msp/dk
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ProMED-mail makes every effort to  verify  the reports  that
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thereon, are not guaranteed. The reader assumes all risks in
using information posted or archived by  ProMED-mail.   ISID
and  its  associated  service  providers  shall not be  held
responsible for errors or omissions or  held liable for  any
damages incurred as a result of use or reliance upon  posted
or archived material.
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Thursday 18 July 2013

Strains of avian H7N9 influenza have developed resistance to antivirals - American Pharmacists Association, pharmacist.com



Strains of avian H7N9 influenza have developed resistance to antivirals - American Pharmacists Association, pharmacist.com
INFLUENZA - GOOGLE NEWS | THU 18 JUL
http://pulse.me/s/oiSKj
Strains of avian H7N9 influenza have developed resistance to antiviralsAmerican Pharmacists Association, pharmacist.comCertain ... Read more

Posted by Rob LW

Sunday 14 July 2013

BioCryst nearly ready to submit new influenza drug to FDA - Vaccine News Daily



BioCryst nearly ready to submit new influenza drug to FDA - Vaccine News Daily
INFLUENZA - GOOGLE NEWS | 13 JULY 2013
http://pulse.me/s/o3abi
BioCryst nearly ready to submit new influenza drug to FDAVaccine News DailyBioCryst Pharmaceuticals, Inc., announced on ... Read more


Thursday 11 July 2013

Virologists Study H7N9's Family Tree to Predict Pandemic Threat



Virologists Study H7N9's Family Tree to Predict Pandemic Threat
DISCOVER MAGAZINE | 9 JULY 2013
http://pulse.me/s/nUrlp


The devil is in the details when it comes to predicting the next viral killer. As a candidate for the next virus most likely to cause a pandemic, inf... Read more

Posted by Rob LW

Sunday 7 July 2013

Tuesday 19 February 2013

Patient Dies From Coronavirus In Birmingham

Patient Dies From Coronavirus In Birmingham

The man, who was already undergoing treatment for a "long-term complex unrelated health condition" before contracting the so-called novel coronavirus, passed away on Sunday morning in the hospital's critical care unit, University Hospitals Birmingham NHS Foundation Trust said.

He is the sixth person to die from the illness worldwide.

The victim had problems with his immune system and is believed to have contracted the coronavirus from a relative who is being treated for the condition in a Manchester hospital. It was the first case of human-to-human transition of the virus in the UK.

He was one of three people in the same family with the virus, which appeared to have been caught by one of the family members during a recent visit to the Middle East and Pakistan.

Sky News Health Correspondent Thomas Moore described coronavirus as "a family of viruses - at one end it is a relatively mild diseases which causes the common cold, but it also causes diseases such as Sars, which is that really nasty respiratory disease that broke out in the Far East a few years back."

"This seems to be much the same kind of serious lung disease, with breathing difficulties, fever and so on," he said.

Moore warned that doctors were "concerned". He added: "At the moment its origins seem to be largely in the Arabian peninsular and surrounding countries but the fact that it has come back to the UK and spread not only to the man who has died but also another relative in the family, who is in a mild condition and being treated at home with antibiotics and being told not to see other people, (is concerning)."

The Health Protection Agency has said the UK population in general is not at risk from the virus at the moment.

A total of 12 cases of the virus have so far been reported to the World Health Organisation with five previous fatalities - three in Saudi Arabia and two in Jordan.




Friday 15 February 2013

BARDA Continues Support of Flublok® and Panblok® Influenza Vaccines -- PEARL RIVER, N.Y., Feb. 15, 2013 /PRNewswire/ --

http://m.prnewswire.com/news-releases/barda-continues-support-of-flublok-and-panblok-influenza-vaccines-191453041.html


Posted by Rob LW

Third Family Member Contracts Sars-Like Virus

Third Family Member Contracts Sars-Like Virus

On Monday, the Health Protection Agency (HPA) said one person who had recently travelled to the Middle East and Pakistan was being treated in an intensive care unit at a Manchester hospital after becoming infected with a new type of coronavirus.

On Wednesday, a relative of the patient who had no recent travel history became infected and now the HPA has said a third person, who has also not travelled recently, is infected.

But the HPA said the risk associated with novel coronavirus to the UK population remained low.

The newest patient is recovering from a mild respiratory illness and is currently well. This latest case brings the total number of confirmed cases globally to 12.

The second family member has an existing medical condition that might have made them more susceptible to respiratory infections, the HPA has said.

Professor John Watson, head of the respiratory diseases department at the HPA, said: "Although this (third) patient had a mild form of respiratory illness, as a precaution the HPA is advising that the patient self-isolate and limit contact with non-household members.

"Follow up of other household members and contacts of this case is currently under way.

"Although this case appears to be due to person-to-person transmission, the risk of infection in contacts in most circumstances is still considered to be low."

Last year British health officials identified another case of the novel coronavirus.

A 49-year-old Qatari man was treated at St Thomas' Hospital in London after becoming infected.

Five patients have died as a result of the infectious disease, none in the UK.

Infected patients have presented with serious respiratory illness with fever, cough, shortness of breath and breathing difficulties.




Tuesday 29 January 2013

NIH-developed candidate dengue vaccine shows promise in early-stage trial, January 23, 2013 News Release - National Institutes of Health (NIH)

http://www.nih.gov/news/health/jan2013/niaid-23.htm

Posted by Rob LW

Dengue Vaccines, one step closer ?

Posted by Rob LW

*Using Twitter to Track the Flu: Researchers Find a Better Way to Screen the Tweets < News from The Johns Hopkins University

http://releases.jhu.edu/2013/01/24/using-twitter-to-track-the-flu/

Posted by Rob LW

*Using Twitter to Track the Flu: Researchers Find a Better Way to Screen the Tweets < News from The Johns Hopkins University

http://releases.jhu.edu/2013/01/24/using-twitter-to-track-the-flu/

Posted by Rob LW

2013 flu epidemic: Tracking influenza spread with Twitter and Google - National health technology | Examiner.com

http://www.examiner.com/article/2013-flu-epidemic-tracking-influenza-spread-with-twitter-and-google

Posted by Rob LW

Monday 14 January 2013

How does influenza spread?

Retroscreen Virology Ltd is part of a CDC grant in which we are trying to understand how influenza virus is spread. One of our colleagues is conducting a study in the USA and shortly we will be conducting a study in the UK.

Professor Don Milton recently gave a series of interviews for US TV and explained how important this work is, see the links below.

Channel 9 story shot at UMD SPH: http://ter.ps/1vv

Channel 7 news story shot at UMD: http://ter.ps/1vx

Channel 5 interview: http://ter.ps/1vw (very brief interview)

Norway Has Most Intense Europe Flu Transmission, EU Says - Bloomberg

http://www.bloomberg.com/news/2013-01-14/norway-has-most-intense-europe-flu-transmission-eu-says.html

Posted by Rob LW

PLOS ONE: A Nice Day for an Infection? Weather Conditions and Social Contact Patterns Relevant to Influenza Transmission

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0048695

Posted by Rob LW

New York declares emergency as flu crisis spreads | The Times

http://www.thetimes.co.uk/tto/news/world/americas/article3656508.ece

Posted by Rob LW

Sunday 13 January 2013

NYC Flu Outbreak Is Public Health Emergency

NYC Flu Outbreak Is Public Health Emergency

Officials are tackling the worst influenza outbreak in several years and an immunisation programme has been expanded to reduce the spread of the illness.

Pharmacists are not usually authorised to vaccinate children under 18 but New York Governor Andrew Cuomo has suspended this order to increase the number of people being protected.

The 20,000 reported cases are more than four times the 4,400 positive laboratory tests reported for the whole of the previous season.

"We are experiencing the worst flu season since at least 2009, and influenza activity in New York state is widespread, with cases reported in all 57 counties and all five boroughs of New York City," Mr Cuomo said in a statement.

"Therefore, I have directed my administration, the State Health Department and others to marshall all needed resources to address this public health emergency."

The flu season in the US got under way a month early, in December, driven by a strain that tends to make people sicker. That led to worries that it might be a bad season, following one of the mildest flu seasons in recent memory.

The latest numbers do show that the flu surpassed an "epidemic" threshold last week. That is based on deaths from pneumonia and influenza in 122 US cities.

The government doesn't keep a running tally of adult deaths from the flu, but estimates that it kills about 24,000 people in an average year. Nationally, 20 children have died from the flu this season.

Flu usually peaks in mid-winter. Symptoms can include fever, cough, runny nose, head and body aches and fatigue. Some people also suffer vomiting and diarrhoea, and some develop pneumonia or other severe complications.     



Posted by Rob LW

Saturday 12 January 2013

Reference "A nice day for an infection? Weather conditions an..."

PLoS ONE, 2012 vol. 7(11) pp. e48695

A nice day for an infection? Weather conditions and social contact patterns relevant to influenza transmission.

Willem, L; Van Kerckhove, K; Chao, DL; Hens, N; Beutels, P

Although there is no doubt that significant morbidity and mortality occur during annual influenza epidemics, the role of contextual circumstances, which catalyze seasonal influenza transmission, remains unclear. Weather conditions are believed to affect virus survival, efficiency of transmission and host immunity, but seasonality may also be driven by a tendency of people to congregate indoors during periods of bad weather. To test this hypothesis, we combined data from a social contact survey in Belgium with local weather data. In the absence of a previous in-depth weather impact analysis of social contact patterns, we explored the possibilities and identified pitfalls. We found general dominance of day-type (weekend, holiday, working day) over weather conditions, but nonetheless observed an increase in long duration contacts ([Formula: see text]1 hour) on regular workdays with low temperatures, almost no precipitation and low absolute humidity of the air. Interestingly, these conditions are often assumed to be beneficial for virus survival and transmission. Further research is needed to establish the impact of the weather on social contacts. We recommend that future studies sample over a broad spectrum of weather conditions and day types and include a sufficiently large proportion of holiday periods and weekends.

PMID: 23155399

PMCID: PMC3498265
URL - http://www.ncbi.nlm.nih.gov/pubmed/23155399?dopt=Citation


Cheers

Rob

Sent from another mobile device with an annoyingly small keyboard, apologies for any typos

YouTube: CDC "a lot of flu out there "

http://m.youtube.com/#/watch?v=PCIiSv6Fi_I&desktop_uri=%2Fwatch%3Fv%3DPCIiSv6Fi_I

Posted by Rob LW

Flu in 47 states but a drop in some states - UPI.com

http://m.upi.com/story/UPI-18381357907834/?pvn=1


Posted by Rob LW

Humidity cause for influenza peak? - UPI.com

http://m.upi.com/story/UPI-95381357944734/

Posted by Rob LW

Influenza: By the numbers

http://edition.cnn.com/2013/01/11/health/flu-numbers/

Posted by Rob LW

Wednesday 9 January 2013

Early Flu Season Is Already Hitting US Hard

Early Flu Season Is Already Hitting US Hard

"The emergency rooms are quite full and it's clear that the annual flu epidemic is in full swing," said Dr Brian Currie, medical director for research at Montefiore Medical Centre in New York.

According to the US Centres for Disease Control and Prevention, the proportion of people visiting doctors for a flu-like illness has climbed from 2.8% to 5.6% in the last month.

That compares with 2.2% during last year's mild flu season, and a peak of 7.7% during the 2009 H1N1 "swine flu" pandemic.

"We are coming to the point where we are running out of testing supplies," said Dr Ed Ward, an expert in emergency and internal medicine at Rush, a teaching hospital.

Dr Daniel Lucey, who tracks global flu activity at Georgetown University Medical Centre in Washington, said the extremely mild nature of last year's flu season is making this year's seem notably worse by comparison.

Even so, he said, "it's an objective fact that flu viruses are circulating earlier and more widely this year than most years."

Experts say it's not clear why the flu arrived earlier than normal in the US this year.

Although each season is unique, flu activity usually starts to pick up in December, peaks sometime in January or February and runs its course by late March or early April.

One risk of an early flu season is that it arrives before people have had a chance to get vaccinated – a precaution that doctors say is by far the best line of defence against infection.

Experts still say it is not too late to get a flu shot.

"We strongly encourage people to get vaccinated, and we'd like them to do that as soon as possible," said Dr Michael Jhung, a CDC flu expert.

So far, 91% of this year's flu viruses analysed by the CDC match flu strains contained in the vaccine, meaning that it should protect people well.

Vaccine coverage has been fairly high so far. By early December, the CDC had vaccinated an estimated 112 million Americans, Dr Jhung said.

People may still get the flu even if they have been vaccinated, but it will likely be less severe.

Dr William Schaffner, an infectious diseases expert at the Vanderbilt University Medical Centre in Nashville, said the flu vaccine was only 70% to 80% effective in healthy young people.

And in older adults, the vaccine only protects about 60% to 65% of those who receive it.



Posted by Rob LW